Guillaume Lessene is the leader of New Medicines and Advanced Technologies Theme at the National Drug Discovery Centre, an initiative of the Walter and Eliza Hall Institute (WEHI) in Parkville, Melbourne. This multidisciplinary research theme comprises of basic research driven by structural and chemical biology, translation of basic discoveries into new medicines together with clinical research, and cutting-edge technologies. The major research focus of Guillaume is the development of small molecules that target apoptotic and necroptotic cell death pathways.