Stefan Knapp is Professor of Chemical Biology at the Goethe University Frankfurt and site head of the Frankfurt node of the “Structure Genomics Consortium”. Stefan’s laboratory is interested in the development and rational design of selective inhibitors targeting key signaling molecules (chemical probes) and their use for the validation of new targets. The research team focusses two main key areas: (1) Targeting protein interactions module that mediate the recognitions of key posttranslational modifications and (2) Targeting protein kinases. His lab is particularly interested in developing inhibitors targeting unusual binding modes and novel allosteric binding sites.